# GO NS enrichment name ratio_in_study ratio_in_pop p_uncorrected depth study_count p_fdr_bh study_items GO:0042802 MF e identical protein binding 49/100 1920/19669 1.1639630231809928e-23 3 49 5.529988323132897e-20 60, 196, 213, 229, 302, 335, 348, 350, 351, 383, 581, 847, 1401, 1510, 1737, 2023, 2081, 2194, 2941, 2944, 2947, 3064, 3075, 3162, 3654, 3934, 4137, 4143, 4199, 4217, 4318, 4831, 4851, 4860, 5071, 5091, 5130, 5468, 5836, 6622, 6652, 7276, 7422, 7450, 7846, 9370, 11035, 26061, 729230 GO:0036094 MF e small molecule binding 39/100 2421/19669 1.0596113031241925e-11 2 39 2.5171066505715193e-08 60, 213, 229, 335, 847, 1152, 1244, 1571, 1719, 2081, 2180, 2194, 3309, 3654, 3934, 4143, 4199, 4217, 4524, 4831, 4846, 4860, 5091, 5166, 5243, 5468, 5580, 5591, 5836, 6652, 6888, 7846, 9131, 9971, 10096, 10383, 11035, 26061, 50507 GO:0043168 MF e anion binding 38/100 2349/19669 1.96298132876536e-11 3 38 2.6568212397602273e-08 60, 213, 302, 1152, 1244, 1719, 2081, 2180, 2934, 2944, 2947, 3309, 3654, 3934, 4143, 4199, 4217, 4524, 4831, 4846, 4860, 5091, 5166, 5243, 5468, 5580, 5591, 5836, 7846, 9131, 9370, 9971, 10096, 10383, 11035, 26061, 50507, 83667 GO:0031072 MF e heat shock protein binding 11/100 119/19669 2.2368522330121885e-11 3 11 2.6568212397602273e-08 196, 335, 581, 1571, 2081, 3064, 3309, 3654, 4137, 5071, 6622 GO:0005102 MF e signaling receptor binding 30/100 1553/19669 8.110731440527411e-11 3 30 7.706817014789147e-08 183, 335, 348, 351, 1401, 1440, 2081, 2243, 2896, 3146, 3440, 3458, 3479, 3553, 3569, 3627, 4851, 5071, 5327, 5468, 5663, 6347, 6696, 7276, 7422, 7450, 9370, 9971, 10383, 729230 GO:0019899 MF e enzyme binding 33/100 1923/19669 1.5452997928216555e-10 3 33 1.223619885949281e-07 60, 229, 302, 335, 351, 847, 1152, 1440, 1571, 2023, 2081, 2934, 2944, 2947, 3064, 3146, 3162, 3309, 4137, 4217, 4831, 4851, 5071, 5243, 5465, 5468, 5580, 5591, 5663, 7450, 23476, 50507, 81631 GO:0043167 MF e ion binding 61/100 5919/19669 1.8414974145346062e-10 2 61 1.2498506023505594e-07 60, 213, 302, 335, 348, 351, 383, 821, 847, 1152, 1244, 1356, 1401, 1559, 1571, 1719, 2023, 2081, 2180, 2243, 2934, 2944, 2947, 3162, 3309, 3654, 3934, 4143, 4199, 4217, 4313, 4318, 4524, 4831, 4846, 4851, 4860, 5071, 5091, 5130, 5166, 5243, 5465, 5468, 5580, 5591, 5836, 6622, 6649, 6652, 7846, 9104, 9131, 9370, 9971, 10096, 10383, 11035, 26061, 50507, 83667 GO:0030546 MF e signaling receptor activator activity 17/100 489/19669 3.9950601248755e-10 3 17 2.3725663316604377e-07 183, 335, 351, 1440, 2896, 3146, 3440, 3458, 3479, 3553, 3569, 3627, 6347, 6696, 7276, 7422, 9370 GO:0005488 MF e binding 100/100 15872/19669 7.666738724863541e-10 1 100 3.7100921558560914e-07 60, 183, 196, 213, 229, 302, 335, 348, 350, 351, 383, 581, 821, 847, 1152, 1244, 1356, 1401, 1440, 1510, 1559, 1571, 1719, 1737, 2023, 2052, 2081, 2180, 2194, 2243, 2876, 2896, 2934, 2941, 2944, 2947, 3030, 3064, 3075, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 3934, 4137, 4143, 4199, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4851, 4860, 5071, 5091, 5130, 5166, 5243, 5327, 5465, 5468, 5580, 5591, 5663, 5836, 6347, 6622, 6649, 6652, 6696, 6888, 7276, 7422, 7450, 7846, 9104, 9131, 9370, 9474, 9971, 10096, 10383, 11035, 23476, 26061, 26762, 50507, 81631, 83667, 136319, 729230 GO:0072341 MF e modified amino acid binding 9/100 90/19669 7.904458498409761e-10 2 9 3.7100921558560914e-07 302, 1719, 2194, 2944, 2947, 3146, 4524, 26762, 50507 GO:0003824 MF e catalytic activity 58/100 5583/19669 8.589983943257631e-10 1 58 3.7100921558560914e-07 229, 383, 847, 1152, 1244, 1356, 1510, 1559, 1571, 1719, 1737, 2023, 2052, 2081, 2180, 2194, 2876, 2941, 2944, 2947, 3030, 3146, 3162, 3309, 3654, 4143, 4199, 4217, 4313, 4318, 4524, 4831, 4846, 4860, 5071, 5091, 5130, 5166, 5243, 5327, 5580, 5591, 5663, 5836, 6347, 6622, 6649, 6652, 6888, 7846, 9104, 9131, 10383, 11035, 23476, 26061, 50507, 83667 GO:0030545 MF e receptor regulator activity 17/100 532/19669 1.4382332434419962e-09 2 17 5.694205116327437e-07 183, 335, 351, 1440, 2896, 3146, 3440, 3458, 3479, 3553, 3569, 3627, 6347, 6696, 7276, 7422, 9370 GO:0005125 MF e cytokine activity 12/100 235/19669 2.656065822734122e-09 5 12 9.376169444041864e-07 1440, 2896, 3146, 3440, 3458, 3553, 3569, 3627, 6347, 6696, 7422, 9370 GO:0048018 MF e receptor ligand activity 16/100 483/19669 2.762920905421724e-09 4 16 9.376169444041864e-07 183, 335, 1440, 2896, 3146, 3440, 3458, 3479, 3553, 3569, 3627, 6347, 6696, 7276, 7422, 9370 GO:0016491 MF e oxidoreductase activity 19/100 740/19669 5.155822900382023e-09 2 19 1.633020973314333e-06 847, 1356, 1559, 1571, 1719, 1737, 2194, 2876, 3030, 3162, 4199, 4524, 4846, 6622, 6649, 6652, 9131, 50507, 83667 GO:0097367 MF e carbohydrate derivative binding 33/100 2213/19669 5.719953146315147e-09 2 33 1.698468587383954e-06 60, 348, 350, 351, 1152, 1244, 2081, 2180, 3075, 3146, 3309, 3627, 3654, 4143, 4199, 4217, 4831, 4846, 4860, 5091, 5166, 5243, 5580, 5591, 5836, 6649, 7422, 7846, 9370, 10096, 10383, 11035, 26061 GO:0044877 MF e protein-containing complex binding 24/100 1230/19669 8.259831999101133e-09 2 24 2.308380107513499e-06 60, 196, 335, 348, 1401, 2934, 3146, 3309, 3440, 3479, 3553, 4137, 4318, 4524, 4831, 5071, 5465, 6622, 6696, 7276, 7450, 10096, 11035, 23476 GO:0005515 MF e protein binding 93/100 13658/19669 1.1798602807665222e-08 2 93 3.1141756632898594e-06 60, 183, 196, 213, 229, 302, 335, 348, 350, 351, 383, 581, 821, 847, 1152, 1244, 1356, 1401, 1440, 1510, 1571, 1737, 2023, 2052, 2081, 2194, 2243, 2876, 2896, 2934, 2941, 2944, 2947, 3030, 3064, 3075, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 3934, 4137, 4143, 4199, 4217, 4313, 4318, 4780, 4831, 4846, 4851, 4860, 5071, 5091, 5130, 5166, 5243, 5327, 5465, 5468, 5580, 5591, 5663, 5836, 6347, 6622, 6649, 6652, 6696, 6888, 7276, 7422, 7450, 7846, 9131, 9370, 9474, 9971, 10096, 10383, 11035, 23476, 26061, 50507, 81631, 83667, 729230 GO:0031406 MF e carboxylic acid binding 10/100 183/19669 3.189123141915092e-08 4 10 7.974486340651896e-06 213, 1719, 4831, 4846, 5091, 5468, 5836, 9370, 9971, 83667 GO:0051087 MF e chaperone binding 8/100 100/19669 4.254422189606372e-08 3 8 1.0106379911409936e-05 213, 581, 1356, 2896, 3309, 4137, 5071, 7450 GO:1901681 MF e sulfur compound binding 11/100 258/19669 8.08564332854818e-08 2 11 1.8292805454253523e-05 348, 350, 351, 2944, 2947, 3075, 3627, 5091, 6649, 7422, 26061 GO:0000166 MF e nucleotide binding 29/100 2103/19669 3.577379847905385e-07 4 29 7.46411293375772e-05 60, 847, 1152, 1244, 1719, 2081, 2180, 3309, 3654, 4143, 4199, 4217, 4524, 4831, 4846, 5091, 5166, 5243, 5580, 5591, 5836, 6652, 7846, 9131, 10096, 10383, 11035, 26061, 50507 GO:1901265 MF e nucleoside phosphate binding 29/100 2104/19669 3.613441327645286e-07 3 29 7.46411293375772e-05 60, 847, 1152, 1244, 1719, 2081, 2180, 3309, 3654, 4143, 4199, 4217, 4524, 4831, 4846, 5091, 5166, 5243, 5580, 5591, 5836, 6652, 7846, 9131, 10096, 10383, 11035, 26061, 50507 GO:0008144 MF e drug binding 6/100 60/19669 5.951199917452989e-07 2 6 0.0001169092272804 213, 1719, 3934, 4831, 5465, 5836 GO:0098772 MF e molecular function regulator 30/100 2287/19669 6.151822104841626e-07 1 30 0.0001169092272804 183, 302, 335, 348, 350, 351, 1440, 2896, 3146, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4831, 4851, 5071, 5580, 6347, 6622, 6696, 7276, 7422, 9104, 9370, 11035, 23476, 83667 GO:0030544 MF e Hsp70 protein binding 5/100 39/19669 1.541549400931022e-06 4 5 0.000266661129792 581, 1571, 2081, 5071, 6622 GO:0008289 MF e lipid binding 16/100 768/19669 1.570612643836725e-06 2 16 0.000266661129792 213, 302, 335, 348, 350, 581, 2934, 3146, 4137, 4831, 5130, 5465, 5468, 6622, 9971, 26762 GO:0033293 MF e monocarboxylic acid binding 6/100 71/19669 1.6274811677906562e-06 5 6 0.000266661129792 213, 4831, 5091, 5468, 5836, 9971 GO:0046914 MF e transition metal ion binding 19/100 1071/19669 1.6276936990046077e-06 5 19 0.000266661129792 213, 351, 383, 1356, 1559, 1571, 3934, 4199, 4313, 4318, 4846, 5071, 5465, 5468, 6622, 6649, 6652, 9104, 9971 GO:0019904 MF e protein domain specific binding 15/100 684/19669 1.8435987861482916e-06 3 15 0.000291964594433 351, 581, 1244, 2876, 3309, 3553, 4137, 4217, 4780, 5071, 5465, 5468, 5591, 5663, 7846 GO:0097159 MF e organic cyclic compound binding 52/100 5883/19669 4.663207193793461e-06 2 52 0.0007146741089584 60, 196, 213, 302, 335, 351, 821, 847, 1152, 1244, 1559, 1571, 1719, 2023, 2081, 2180, 2194, 2896, 3146, 3162, 3309, 3654, 3934, 4137, 4143, 4199, 4217, 4524, 4780, 4831, 4846, 4851, 4860, 5091, 5166, 5243, 5465, 5468, 5580, 5591, 5836, 6622, 6652, 7846, 9131, 9971, 10096, 10383, 11035, 26061, 50507, 136319 GO:0016209 MF e antioxidant activity 6/100 86/19669 5.024506237138656e-06 1 6 0.0007459821603951 213, 348, 847, 2876, 6649, 83667 GO:0042803 MF e protein homodimerization activity 14/100 659/19669 6.053741383896911e-06 4 14 0.0008715553125725 196, 348, 581, 847, 2023, 2081, 2941, 2944, 2947, 3162, 3654, 4217, 7422, 9370 GO:0050661 MF e NADP binding 5/100 52/19669 6.604041268449777e-06 5 5 0.0009228176490119 847, 1719, 4199, 4524, 4846 GO:1901363 MF e heterocyclic compound binding 51/100 5803/19669 7.47001721048855e-06 2 51 0.001014001479058 60, 196, 213, 302, 351, 821, 847, 1152, 1244, 1559, 1571, 1719, 2023, 2081, 2180, 2194, 2896, 3146, 3162, 3309, 3654, 3934, 4137, 4143, 4199, 4217, 4524, 4780, 4831, 4846, 4851, 4860, 5091, 5166, 5243, 5465, 5468, 5580, 5591, 5836, 6622, 6652, 7846, 9131, 9971, 10096, 10383, 11035, 26061, 50507, 136319 GO:0070851 MF e growth factor receptor binding 7/100 141/19669 7.694344361225808e-06 4 7 0.0010154397238939 351, 1440, 2081, 3553, 3569, 5663, 7422 GO:0005126 MF e cytokine receptor binding 9/100 270/19669 9.694473943747218e-06 4 9 0.0012159874479864 1440, 3440, 3458, 3553, 3569, 3627, 6347, 7422, 729230 GO:0003674 MF e molecular_function 100/100 17455/19669 9.725852036094849e-06 0 100 0.0012159874479864 60, 183, 196, 213, 229, 302, 335, 348, 350, 351, 383, 581, 821, 847, 1152, 1244, 1356, 1401, 1440, 1510, 1559, 1571, 1719, 1737, 2023, 2052, 2081, 2180, 2194, 2243, 2876, 2896, 2934, 2941, 2944, 2947, 3030, 3064, 3075, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 3934, 4137, 4143, 4199, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4851, 4860, 5071, 5091, 5130, 5166, 5243, 5327, 5465, 5468, 5580, 5591, 5663, 5836, 6347, 6622, 6649, 6652, 6696, 6888, 7276, 7422, 7450, 7846, 9104, 9131, 9370, 9474, 9971, 10096, 10383, 11035, 23476, 26061, 26762, 50507, 81631, 83667, 136319, 729230 GO:0071814 MF e protein-lipid complex binding 4/100 28/19669 1.1725507194213829e-05 3 4 0.0013926971169927 335, 348, 1401, 4137 GO:0071813 MF e lipoprotein particle binding 4/100 28/19669 1.1725507194213829e-05 4 4 0.0013926971169927 335, 348, 1401, 4137 GO:0008201 MF e heparin binding 7/100 164/19669 2.0587783867855883e-05 4 7 0.0023856722233215 348, 350, 351, 3075, 3627, 6649, 7422 GO:1903981 MF e enterobactin binding 2/100 2/19669 2.559132160840943e-05 4 2 0.0028275434642221 213, 3934 GO:0016418 MF e S-acetyltransferase activity 2/100 2/19669 2.559132160840943e-05 6 2 0.0028275434642221 1737, 2194 GO:0043169 MF e cation binding 40/100 4263/19669 4.170485821846842e-05 3 40 0.0045031768499078 213, 302, 335, 348, 351, 383, 821, 847, 1356, 1401, 1559, 1571, 2023, 2081, 2243, 2934, 3162, 3309, 3934, 4143, 4199, 4217, 4313, 4318, 4831, 4846, 4851, 5071, 5091, 5130, 5465, 5468, 5580, 5836, 6622, 6649, 6652, 9104, 9971, 26061 GO:0051879 MF e Hsp90 protein binding 4/100 40/19669 4.994451325481218e-05 4 4 0.0052730307216358 196, 1571, 2081, 4137 GO:0032553 MF e ribonucleotide binding 23/100 1875/19669 5.232842939853182e-05 5 23 0.0054046166972266 60, 1152, 1244, 2081, 2180, 3309, 3654, 4143, 4199, 4217, 4831, 4846, 5091, 5166, 5243, 5580, 5591, 5836, 7846, 10096, 10383, 11035, 26061 GO:0016829 MF e lyase activity 7/100 193/19669 5.823316092161888e-05 2 7 0.0058865052667789 229, 2023, 2194, 3030, 3146, 4199, 26061 GO:0032559 MF e adenyl ribonucleotide binding 20/100 1516/19669 6.600691986097257e-05 7 20 0.0065333099220725 60, 1152, 1244, 2081, 2180, 3309, 3654, 4143, 4199, 4217, 4831, 5091, 5166, 5243, 5580, 5591, 5836, 10096, 11035, 26061 GO:0020037 MF e heme binding 6/100 138/19669 7.424534021581727e-05 4 6 0.0070608133248553 847, 1559, 1571, 3162, 4846, 50507 GO:0030554 MF e adenyl nucleotide binding 20/100 1529/19669 7.430870684966676e-05 6 20 0.0070608133248553 60, 1152, 1244, 2081, 2180, 3309, 3654, 4143, 4199, 4217, 4831, 5091, 5166, 5243, 5580, 5591, 5836, 10096, 11035, 26061 GO:0002060 MF e purine nucleobase binding 2/100 3/19669 7.651892343145596e-05 4 2 0.0071282628475068 4860, 5836 GO:0019842 MF e vitamin binding 6/100 143/19669 9.041612194005348e-05 3 6 0.0082609037564845 213, 1719, 2194, 5091, 5836, 26061 GO:0050839 MF e cell adhesion molecule binding 11/100 540/19669 9.4102131809922e-05 3 11 0.0083184016523354 302, 2023, 2194, 2243, 3146, 3309, 3479, 3553, 5663, 6696, 7450 GO:0005543 MF e phospholipid binding 10/100 448/19669 9.45471877975408e-05 3 10 0.0083184016523354 302, 335, 348, 350, 2934, 3146, 4137, 5130, 6622, 26762 GO:0046906 MF e tetrapyrrole binding 6/100 148/19669 0.0001092751209271 3 6 0.0094393836277222 847, 1559, 1571, 3162, 4846, 50507 GO:0005524 MF e ATP binding 19/100 1455/19669 0.0001186600875473 8 19 0.0100670370703131 60, 1152, 1244, 2081, 2180, 3309, 3654, 4143, 4217, 4831, 5091, 5166, 5243, 5580, 5591, 5836, 10096, 11035, 26061 GO:0033218 MF e amide binding 9/100 377/19669 0.0001300711585685 2 9 0.0108415451641927 335, 348, 847, 1719, 2194, 2944, 2947, 5091, 5468 GO:0098531 MF e ligand-activated transcription factor activity 4/100 52/19669 0.0001411984713549 3 4 0.0113700667357152 196, 5465, 5468, 9971 GO:0004879 MF e nuclear receptor activity 4/100 52/19669 0.0001411984713549 4 4 0.0113700667357152 196, 5465, 5468, 9971 GO:0005539 MF e glycosaminoglycan binding 7/100 227/19669 0.0001602423139755 3 7 0.0126885205616297 348, 350, 351, 3075, 3627, 6649, 7422 GO:0008083 MF e growth factor activity 6/100 161/19669 0.0001731923354625 5 6 0.0134891276357817 183, 1440, 2896, 3479, 3569, 7422 GO:0032555 MF e purine ribonucleotide binding 22/100 1859/19669 0.0001813808493386 6 22 0.0138990389549684 60, 1152, 1244, 2081, 2180, 3309, 3654, 4143, 4199, 4217, 4831, 5091, 5166, 5243, 5580, 5591, 5836, 7846, 10096, 10383, 11035, 26061 GO:0017076 MF e purine nucleotide binding 22/100 1874/19669 0.0001940688723265 5 22 0.0146352573400517 60, 1152, 1244, 2081, 2180, 3309, 3654, 4143, 4199, 4217, 4831, 5091, 5166, 5243, 5580, 5591, 5836, 7846, 10096, 10383, 11035, 26061 GO:0016765 MF e transferase activity, transferring alkyl or aryl (other than methyl) groups 4/100 57/19669 0.000202053287886 3 4 0.0149992995429151 2941, 2944, 2947, 4143 GO:0046983 MF e protein dimerization activity 15/100 1027/19669 0.0002072289512431 3 15 0.0151468422670167 196, 348, 581, 847, 2023, 2081, 2941, 2944, 2947, 3162, 3654, 4217, 7422, 9131, 9370 GO:0005507 MF e copper ion binding 4/100 58/19669 0.0002161782805203 6 4 0.0155615607689723 213, 1356, 6622, 6649 GO:0002054 MF e nucleobase binding 2/100 5/19669 0.0002533722245622 3 2 0.0179667378939563 4860, 5836 GO:0043177 MF e organic acid binding 5/100 113/19669 0.000279272912601 3 5 0.0195121412906969 1719, 4846, 5091, 5468, 9971 GO:0035639 MF e purine ribonucleoside triphosphate binding 21/100 1791/19669 0.0002927734125597 4 21 0.0201589345372672 60, 1152, 1244, 2081, 2180, 3309, 3654, 4143, 4217, 4831, 5091, 5166, 5243, 5580, 5591, 5836, 7846, 10096, 10383, 11035, 26061 GO:0004364 MF e glutathione transferase activity 3/100 26/19669 0.0003045224989504 4 3 0.0206683770359067 2941, 2944, 2947 GO:0046872 MF e metal ion binding 37/100 4177/19669 0.0003099183972226 4 37 0.0207383423268264 213, 302, 348, 351, 383, 821, 847, 1356, 1401, 1559, 1571, 2023, 2081, 2243, 2934, 3162, 3309, 3934, 4143, 4199, 4217, 4313, 4318, 4831, 4846, 4851, 5071, 5091, 5465, 5468, 5580, 6622, 6649, 6652, 9104, 9971, 26061 GO:0004704 MF e NF-kappaB-inducing kinase activity 2/100 6/19669 0.0003787972267494 3 2 0.02412739769036 3654, 11035 GO:0031727 MF e CCR2 chemokine receptor binding 2/100 6/19669 0.0003787972267494 7 2 0.02412739769036 6347, 729230 GO:0060228 MF e phosphatidylcholine-sterol O-acyltransferase activator activity 2/100 6/19669 0.0003787972267494 4 2 0.02412739769036 335, 348 GO:0070325 MF e lipoprotein particle receptor binding 3/100 28/19669 0.0003808787259054 4 3 0.02412739769036 335, 348, 1401 GO:0016775 MF e phosphotransferase activity, nitrogenous group as acceptor 2/100 7/19669 0.0005285570904716 4 2 0.0330417728530391 1152, 4831 GO:0004672 MF e protein kinase activity 10/100 560/19669 0.000562698893292 5 10 0.0347192524939042 2081, 3654, 4217, 4831, 5166, 5580, 5591, 6347, 11035, 23476 GO:0016174 MF e NAD(P)H oxidase H2O2-forming activity 2/100 8/19669 0.000702406087053 5 2 0.0427837348665266 9131, 50507 GO:0016740 MF e transferase activity 23/100 2218/19669 0.0007130529363132 2 23 0.0428824620306855 1152, 1737, 2081, 2194, 2941, 2944, 2947, 3030, 3654, 4143, 4217, 4831, 4860, 5071, 5130, 5166, 5580, 5591, 5836, 6347, 6888, 11035, 23476 GO:0050660 MF e flavin adenine dinucleotide binding 4/100 81/19669 0.0007753373893639 5 4 0.0460453492108497 4524, 4846, 9131, 50507 GO:0005178 MF e integrin binding 5/100 142/19669 0.000793970124115 4 5 0.0465697785144542 3146, 3479, 3553, 6696, 7450 GO:0005504 MF e fatty acid binding 3/100 37/19669 0.0008739094202008 6 3 0.0500234175346272 213, 4831, 5468 GO:0042056 MF e chemoattractant activity 3/100 37/19669 0.0008739094202008 5 3 0.0500234175346272 3146, 3627, 7422 GO:0019825 MF e oxygen binding 3/100 38/19669 0.0009453311951136 3 3 0.053467482237914 213, 1571, 50507 GO:0016301 MF e kinase activity 11/100 721/19669 0.0010883451015026 4 11 0.060832089143991 1152, 2081, 3654, 4217, 4831, 5166, 5580, 5591, 6347, 11035, 23476 GO:0030234 MF e enzyme regulator activity 15/100 1212/19669 0.0011650996098931 2 15 0.0643649796116531 183, 302, 335, 348, 350, 351, 3146, 3627, 3654, 4851, 5580, 6622, 9104, 11035, 83667 GO:0008092 MF e cytoskeletal protein binding 13/100 967/19669 0.0012185181450992 3 13 0.0665422954869728 60, 229, 302, 348, 2934, 3064, 4137, 4846, 5071, 5468, 6622, 10096, 81631 GO:0008559 MF e ABC-type xenobiotic transporter activity 2/100 11/19669 0.0013660579081928 10 2 0.0729229339530795 1244, 5243 GO:0032052 MF e bile acid binding 2/100 11/19669 0.0013660579081928 6 2 0.0729229339530795 5836, 9971 GO:0048156 MF e tau protein binding 3/100 44/19669 0.0014517304957866 4 3 0.0766352398386953 60, 348, 6622 GO:0016772 MF e transferase activity, transferring phosphorus-containing groups 12/100 866/19669 0.0014696610313997 3 12 0.0767292259360453 1152, 2081, 3654, 4217, 4831, 5130, 5166, 5580, 5591, 6347, 11035, 23476 GO:0004674 MF e protein serine/threonine kinase activity 8/100 427/19669 0.0015083076703099 6 8 0.0778909754526388 2081, 3654, 4217, 4831, 5580, 5591, 11035, 23476 GO:0005527 MF e macrolide binding 2/100 12/19669 0.0016338424951994 3 2 0.0817093231020253 213, 3934 GO:0043295 MF e glutathione binding 2/100 12/19669 0.0016338424951994 5 2 0.0817093231020253 2944, 2947 GO:0034452 MF e dynactin binding 2/100 12/19669 0.0016338424951994 4 2 0.0817093231020253 3064, 4137 GO:0005200 MF e structural constituent of cytoskeleton 4/100 102/19669 0.0018258396307382 2 4 0.090360042558723 60, 7846, 10096, 10383 GO:0016709 MF e oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 3/100 48/19669 0.0018682390132759 4 3 0.0915051912584958 1559, 1571, 4846 GO:1900750 MF e oligopeptide binding 2/100 13/19669 0.0019245147277365 4 2 0.0932996884844506 2944, 2947 GO:0016773 MF e phosphotransferase activity, alcohol group as acceptor 10/100 662/19669 0.0019832443531259 4 10 0.0951756961788024 2081, 3654, 4217, 4831, 5166, 5580, 5591, 6347, 11035, 23476 GO:0016830 MF e carbon-carbon lyase activity 3/100 50/19669 0.0021016234494815 3 3 0.0998481300848661 229, 4199, 26061 GO:0051082 MF e unfolded protein binding 4/100 110/19669 0.0024050084603333 3 4 0.1131306454954827 821, 2081, 3309, 10383 GO:0005161 MF e platelet-derived growth factor receptor binding 2/100 15/19669 0.0025735840915117 5 2 0.1187096895026426 2081, 7422 GO:0008392 MF e arachidonic acid epoxygenase activity 2/100 15/19669 0.0025735840915117 5 2 0.1187096895026426 1559, 1571 GO:0050664 MF e oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/100 16/19669 0.0029315165819524 4 2 0.1339195700082338 9131, 50507 GO:0016684 MF e oxidoreductase activity, acting on peroxide as acceptor 3/100 57/19669 0.0030579229332411 3 3 0.1383637319602728 847, 2876, 83667 GO:0016616 MF e oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/100 119/19669 0.0031951252534339 4 4 0.1430226965347487 2194, 3030, 4199, 6652 GO:0005179 MF e hormone activity 4/100 120/19669 0.0032925877738057 5 4 0.1430226965347487 183, 3479, 7276, 9370 GO:0046965 MF e retinoid X receptor binding 2/100 17/19669 0.0033114074129283 8 2 0.1430226965347487 5468, 9971 GO:0055102 MF e lipase inhibitor activity 2/100 17/19669 0.0033114074129283 4 2 0.1430226965347487 302, 335 GO:0043395 MF e heparan sulfate proteoglycan binding 2/100 17/19669 0.0033114074129283 4 2 0.1430226965347487 348, 3075 GO:0001786 MF e phosphatidylserine binding 3/100 59/19669 0.0033726732428411 4 3 0.1443564916823278 302, 3146, 26762 GO:0001221 MF e transcription coregulator binding 3/100 61/19669 0.0037065713973481 4 3 0.1561114941371284 196, 4780, 5465 GO:0016646 MF e oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/100 18/19669 0.0037130285913482 4 2 0.1561114941371284 1719, 4524 GO:0008391 MF e arachidonic acid monooxygenase activity 2/100 19/19669 0.004136153833314 4 2 0.1632078466236653 1559, 1571 GO:0016836 MF e hydro-lyase activity 3/100 64/19669 0.0042440839296606 4 3 0.1632078466236653 2023, 2194, 3030 GO:0016614 MF e oxidoreductase activity, acting on CH-OH group of donors 4/100 129/19669 0.0042624769383238 3 4 0.1632078466236653 2194, 3030, 4199, 6652 GO:0042277 MF e peptide binding 6/100 304/19669 0.0045936634355794 3 6 0.1632078466236653 335, 348, 847, 2944, 2947, 5468 GO:0000287 MF e magnesium ion binding 5/100 214/19669 0.0047485710563099 5 5 0.1632078466236653 2023, 2081, 4217, 6622, 26061 GO:0048029 MF e monosaccharide binding 3/100 67/19669 0.0048265804190396 3 3 0.1632078466236653 229, 5836, 6888 GO:0120020 MF e cholesterol transfer activity 2/100 21/19669 0.0050460198582378 5 2 0.1632078466236653 335, 348 GO:0042379 MF e chemokine receptor binding 3/100 69/19669 0.0052404170948103 5 3 0.1670954470969395 3627, 6347, 729230 GO:0120015 MF e sterol transfer activity 2/100 22/19669 0.0055323165254687 4 2 0.17406646233445 335, 348 GO:0140359 MF e ABC-type transporter activity 2/100 22/19669 0.0055323165254687 9 2 0.17406646233445 1244, 5243 GO:0070491 MF e repressing transcription factor binding 3/100 71/19669 0.0056749960744232 5 3 0.1773809628262153 3146, 5465, 5468 GO:0050750 MF e low-density lipoprotein particle receptor binding 2/100 23/19669 0.0060392290021592 5 2 0.1875318757467886 348, 1401 GO:0004190 MF e aspartic-type endopeptidase activity 2/100 24/19669 0.0065665393896087 5 2 0.2025820041560461 1510, 5663 GO:0005506 MF e iron ion binding 4/100 147/19669 0.0067459290592098 6 4 0.2067736061955226 1559, 1571, 3934, 6622 GO:0070330 MF e aromatase activity 2/100 25/19669 0.0071140314326363 5 2 0.2152787473659588 1559, 1571 GO:0070001 MF e aspartic-type peptidase activity 2/100 25/19669 0.0071140314326363 4 2 0.2152787473659588 1510, 5663 GO:0005198 MF e structural molecule activity 9/100 672/19669 0.0072245024639504 1 9 0.2172380456090428 60, 348, 2243, 3162, 7450, 7846, 9370, 10096, 10383 GO:0016835 MF e carbon-oxygen lyase activity 3/100 79/19669 0.0076259706273854 3 3 0.2266755367362984 2023, 2194, 3030 GO:0001223 MF e transcription coactivator binding 2/100 26/19669 0.0076814905103228 5 2 0.2266755367362984 196, 5465 GO:0042974 MF e retinoic acid receptor binding 2/100 26/19669 0.0076814905103228 7 2 0.2266755367362984 5468, 9971 GO:0008270 MF e zinc ion binding 10/100 810/19669 0.008147072948832 6 10 0.238930515925315 213, 4313, 4318, 5071, 5465, 5468, 6622, 6652, 9104, 9971 GO:0106310 MF e protein serine kinase activity 5/100 248/19669 0.0087329267995369 7 5 0.2447069184323456 2081, 3654, 5580, 5591, 11035 GO:0016645 MF e oxidoreductase activity, acting on the CH-NH group of donors 2/100 28/19669 0.0088754593849333 3 2 0.2447069184323456 1719, 4524 GO:0016705 MF e oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/100 160/19669 0.0090378345092523 3 4 0.2447069184323456 1559, 1571, 3162, 4846 GO:0042910 MF e xenobiotic transmembrane transporter activity 2/100 29/19669 0.0095015480084472 3 2 0.2447069184323456 1244, 5243 GO:0031210 MF e phosphatidylcholine binding 2/100 30/19669 0.0101467612989206 4 2 0.2447069184323456 335, 5130 GO:0050997 MF e quaternary ammonium group binding 2/100 30/19669 0.0101467612989206 2 2 0.2447069184323456 335, 5130 GO:0003713 MF e transcription coactivator activity 5/100 259/19669 0.0104063708413033 3 5 0.24970034276279 3146, 4831, 4851, 11035, 23476 GO:0016417 MF e S-acyltransferase activity 2/100 32/19669 0.0114937369880352 5 2 0.2744057509053027 1737, 2194 GO:0030246 MF e carbohydrate binding 5/100 266/19669 0.0115789409243975 2 5 0.2750577416590634 229, 821, 5836, 6652, 6888 GO:0019956 MF e chemokine binding 2/100 33/19669 0.0121950908555297 4 2 0.2844540313958026 3146, 729230 GO:0031624 MF e ubiquitin conjugating enzyme binding 2/100 33/19669 0.0121950908555297 5 2 0.2844540313958026 5071, 5465 GO:0071949 MF e FAD binding 2/100 33/19669 0.0121950908555297 6 2 0.2844540313958026 4524, 9131 GO:0004866 MF e endopeptidase inhibitor activity 4/100 175/19669 0.0122524853621403 5 4 0.2844540313958026 183, 302, 351, 6622 GO:0140297 MF e DNA-binding transcription factor binding 6/100 375/19669 0.0122738531753608 4 6 0.2844540313958026 60, 3146, 4780, 5465, 5468, 9971 GO:0061629 MF e RNA polymerase II-specific DNA-binding transcription factor binding 5/100 271/19669 0.0124696923867748 5 5 0.2875898472309101 60, 4780, 5465, 5468, 9971 GO:0004857 MF e enzyme inhibitor activity 6/100 377/19669 0.0125731721080579 3 6 0.2876432692556268 183, 302, 335, 351, 4851, 6622 GO:0016407 MF e acetyltransferase activity 3/100 95/19669 0.012593096191364 5 3 0.2876432692556268 1737, 2194, 3030 GO:0015248 MF e sterol transporter activity 2/100 34/19669 0.0129147523048608 3 2 0.2916394216199257 335, 348 GO:0016712 MF e oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/100 34/19669 0.0129147523048608 4 2 0.2916394216199257 1559, 1571 GO:0004867 MF e serine-type endopeptidase inhibitor activity 3/100 96/19669 0.0129522033175761 6 3 0.2916394216199257 183, 302, 351 GO:0001103 MF e RNA polymerase II repressing transcription factor binding 2/100 35/19669 0.0136525209385889 6 2 0.3017895988970461 5465, 5468 GO:0030414 MF e peptidase inhibitor activity 4/100 181/19669 0.0137192816345256 4 4 0.3017895988970461 183, 302, 351, 6622 GO:0043394 MF e proteoglycan binding 2/100 36/19669 0.0144081978868115 3 2 0.3017895988970461 348, 3075 GO:0000217 MF e DNA secondary structure binding 2/100 36/19669 0.0144081978868115 5 2 0.3017895988970461 3146, 4137 GO:0004497 MF e monooxygenase activity 3/100 100/19669 0.0144469889598269 3 3 0.3017895988970461 1559, 1571, 4846 GO:0008134 MF e transcription factor binding 8/100 631/19669 0.015108441043634 3 8 0.3017895988970461 60, 196, 3146, 4780, 5465, 5468, 5591, 9971 GO:0008395 MF e steroid hydroxylase activity 2/100 37/19669 0.015181585800125 4 2 0.3017895988970461 1559, 1571 GO:0061135 MF e endopeptidase regulator activity 4/100 187/19669 0.0152934556872903 4 4 0.3027466998763188 183, 302, 351, 6622 GO:0001664 MF e G protein-coupled receptor binding 5/100 287/19669 0.0156305479932001 4 5 0.3081358237165722 183, 3627, 5071, 6347, 729230 GO:1902936 MF e phosphatidylinositol bisphosphate binding 3/100 104/19669 0.0160356985526329 6 3 0.3148165447254508 302, 2934, 4137 GO:0031625 MF e ubiquitin protein ligase binding 5/100 290/19669 0.0162776088117485 5 5 0.3182506973852561 1152, 3309, 5071, 5243, 81631 GO:0019894 MF e kinesin binding 2/100 39/19669 0.0167807126444461 4 2 0.3240860397307461 60, 6622 GO:0043531 MF e ADP binding 2/100 39/19669 0.0167807126444461 8 2 0.3240860397307461 2081, 4199 GO:0044390 MF e ubiquitin-like protein conjugating enzyme binding 2/100 39/19669 0.0167807126444461 4 2 0.3240860397307461 5071, 5465 GO:0019902 MF e phosphatase binding 4/100 193/19669 0.016977382236825 4 4 0.326556854279982 4137, 4217, 5465, 5468 GO:0044389 MF e ubiquitin-like protein ligase binding 5/100 308/19669 0.0205371887901515 4 5 0.3709968971179089 1152, 3309, 5071, 5243, 81631 GO:0120013 MF e lipid transfer activity 2/100 45/19669 0.0219830948925297 3 2 0.3956124387667001 335, 348 GO:0048020 MF e CCR chemokine receptor binding 2/100 46/19669 0.0229072463204458 6 2 0.4106880274280692 6347, 729230 GO:0070888 MF e E-box binding 2/100 47/19669 0.0238472165420998 10 2 0.4259328037275054 196, 5468 GO:0003779 MF e actin binding 6/100 437/19669 0.0241132055141964 4 6 0.4270143085344057 2934, 4137, 4846, 5071, 6622, 10096 GO:0008009 MF e chemokine activity 2/100 49/19669 0.0257738895811364 6 2 0.4357713501778615 3627, 6347 GO:0017124 MF e SH3 domain binding 3/100 127/19669 0.0270146759500083 4 3 0.45458635151375 2876, 4137, 5071 GO:0061134 MF e peptidase regulator activity 4/100 223/19669 0.0271119225419932 3 4 0.45458635151375 183, 302, 351, 6622 GO:0005509 MF e calcium ion binding 8/100 705/19669 0.0272113310017891 5 8 0.45458635151375 302, 821, 1401, 2934, 3309, 4851, 6622, 9104 GO:0045296 MF e cadherin binding 5/100 332/19669 0.0272694401560553 4 5 0.45458635151375 302, 2023, 2194, 3309, 5663 GO:0002020 MF e protease binding 3/100 130/19669 0.0286790313014472 4 3 0.4738969355536422 302, 5071, 7450 GO:0051287 MF e NAD binding 2/100 53/19669 0.0298091775491543 5 2 0.4738969355536422 4199, 6652 GO:0004601 MF e peroxidase activity 2/100 53/19669 0.0298091775491543 4 2 0.4738969355536422 847, 2876 GO:0016597 MF e amino acid binding 2/100 54/19669 0.0308548808848184 5 2 0.4806279969959747 4846, 83667 GO:0070279 MF e vitamin B6 binding 2/100 54/19669 0.0308548808848184 4 2 0.4806279969959747 213, 5836 GO:0030170 MF e pyridoxal phosphate binding 2/100 54/19669 0.0308548808848184 5 2 0.4806279969959747 213, 5836 GO:0001099 MF e basal RNA polymerase II transcription machinery binding 2/100 55/19669 0.0319149913756998 4 2 0.4922991039803576 196, 23476 GO:0050840 MF e extracellular matrix binding 2/100 55/19669 0.0319149913756998 2 2 0.4922991039803576 6696, 7422 GO:0001098 MF e basal transcription machinery binding 2/100 55/19669 0.0319149913756998 3 2 0.4922991039803576 196, 23476 GO:0019900 MF e kinase binding 8/100 735/19669 0.0336476482947045 4 8 0.5173462040392921 60, 2934, 3064, 4137, 4217, 5071, 5580, 50507 GO:0042626 MF e ATPase-coupled transmembrane transporter activity 2/100 58/19669 0.0351800690394518 8 2 0.5206869408300172 1244, 5243 GO:0003712 MF e transcription coregulator activity 6/100 481/19669 0.0360890269738284 2 6 0.5324812644492513 3146, 4831, 4851, 5071, 11035, 23476 GO:0106311 MF e protein threonine kinase activity 4/100 247/19669 0.0373613167062084 7 4 0.5495467977436425 2081, 3654, 5591, 11035 GO:0015631 MF e tubulin binding 5/100 363/19669 0.0378511776164622 4 5 0.5550337804191737 3064, 4137, 5071, 6622, 81631 GO:0015399 MF e primary active transmembrane transporter activity 2/100 61/19669 0.0385687581683813 4 2 0.5617380099044375 1244, 5243 GO:0030145 MF e manganese ion binding 2/100 62/19669 0.0397250230699007 6 2 0.5617380099044375 383, 4199 GO:0019903 MF e protein phosphatase binding 3/100 148/19669 0.0397797787662478 5 3 0.5617380099044375 4137, 4217, 5468 GO:0002039 MF e p53 binding 2/100 66/19669 0.0444793010113596 3 2 0.6211846390548842 3064, 23476 GO:0005518 MF e collagen binding 2/100 68/19669 0.0469317623323606 3 2 0.6481767524448995 4318, 7450 GO:0005319 MF e lipid transporter activity 3/100 160/19669 0.0482222974579984 2 3 0.6505465416006947 335, 348, 5243 GO:0004252 MF e serine-type endopeptidase activity 3/100 160/19669 0.0482222974579984 5 3 0.6505465416006947 4313, 4318, 5327 GO:0008047 MF e enzyme activator activity 6/100 533/19669 0.054513279484511 3 6 0.6946761929238205 335, 348, 350, 351, 3146, 5580 GO:0005201 MF e extracellular matrix structural constituent 3/100 170/19669 0.0558746804293121 2 3 0.7097877185017707 2243, 7450, 9370 GO:0003725 MF e double-stranded RNA binding 2/100 76/19669 0.0572151682576866 5 2 0.7248780383793846 3146, 10383 GO:1901981 MF e phosphatidylinositol phosphate binding 3/100 172/19669 0.057470863485565 5 3 0.7261810436699984 302, 2934, 4137 GO:0140272 MF e exogenous protein binding 2/100 77/19669 0.0585514170007986 2 2 0.736199443127286 213, 26762 GO:0033613 MF e activating transcription factor binding 2/100 78/19669 0.0598984760404211 5 2 0.7410876553855231 4780, 5468 GO:0008236 MF e serine-type peptidase activity 3/100 178/19669 0.062388157397917 4 3 0.7698860670065032 4313, 4318, 5327 GO:0005546 MF e phosphatidylinositol-4,5-bisphosphate binding 2/100 80/19669 0.062624458449734 7 2 0.7708000054266486 302, 2934 GO:0017171 MF e serine hydrolase activity 3/100 180/19669 0.0640696461766997 3 3 0.7832891297819093 4313, 4318, 5327 GO:0030165 MF e PDZ domain binding 2/100 83/19669 0.0667909979095039 4 2 0.8136513617129575 5071, 5663 GO:0001540 MF e amyloid-beta binding 2/100 84/19669 0.0681999778005683 4 2 0.8183001200590807 335, 348 GO:0008013 MF e beta-catenin binding 2/100 84/19669 0.0681999778005683 3 2 0.8183001200590807 5071, 5663 GO:0004175 MF e endopeptidase activity 5/100 430/19669 0.0683688002174204 4 5 0.8183001200590807 1510, 4313, 4318, 5327, 5663 GO:0051117 MF e ATPase binding 2/100 85/19669 0.0696187981172229 4 2 0.8248351866706386 229, 5663 GO:0019887 MF e protein kinase regulator activity 3/100 188/19669 0.0710031677939106 4 3 0.8391444034548986 3146, 3627, 6622 GO:0051219 MF e phosphoprotein binding 2/100 87/19669 0.0724854246006633 3 2 0.8532358227740054 5327, 6622 GO:0140096 MF e catalytic activity, acting on a protein 17/100 2227/19669 0.0806379892198289 2 17 0.920940112460114 1510, 1737, 2081, 3654, 4217, 4313, 4318, 4831, 5071, 5166, 5327, 5580, 5591, 5663, 6347, 11035, 23476 GO:0016922 MF e nuclear receptor binding 2/100 97/19669 0.0873644446753661 7 2 0.968996857603044 5468, 9971 GO:0005496 MF e steroid binding 2/100 100/19669 0.0919932853904139 3 2 1.0 335, 9971 GO:0031490 MF e chromatin DNA binding 2/100 102/19669 0.0951184812713123 5 2 1.0 60, 4851 GO:0016651 MF e oxidoreductase activity, acting on NAD(P)H 2/100 102/19669 0.0951184812713123 3 2 1.0 9131, 50507 GO:0019207 MF e kinase regulator activity 3/100 218/19669 0.0997906713851047 3 3 1.0 3146, 3627, 6622 GO:0004222 MF e metalloendopeptidase activity 2/100 107/19669 0.1030622227977693 5 2 1.0 4313, 4318 GO:0016747 MF e transferase activity, transferring acyl groups other than amino-acyl groups 3/100 224/19669 0.1060381037303251 4 3 1.0 1737, 2194, 3030 GO:0003697 MF e single-stranded DNA binding 2/100 113/19669 0.1128251356622825 5 2 1.0 3146, 4137 GO:0005262 MF e calcium channel activity 2/100 116/19669 0.1177939805870555 8 2 1.0 302, 5663 GO:0016810 MF e hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/100 121/19669 0.1261950673848805 3 2 1.0 383, 847 GO:0016787 MF e hydrolase activity 18/100 2484/19669 0.1286126230761782 2 18 1.0 383, 847, 1244, 1510, 2052, 2081, 2180, 2194, 3162, 3309, 4313, 4318, 5243, 5327, 5663, 7846, 9104, 10383 GO:0001882 MF e nucleoside binding 4/100 385/19669 0.1329598803299746 3 4 1.0 4831, 4860, 7846, 10383 GO:0016746 MF e transferase activity, transferring acyl groups 3/100 251/19669 0.135932111769312 3 3 1.0 1737, 2194, 3030 GO:0035091 MF e phosphatidylinositol binding 3/100 253/19669 0.1382533836901117 4 3 1.0 302, 2934, 4137 GO:0015085 MF e calcium ion transmembrane transporter activity 2/100 132/19669 0.1451486232336259 7 2 1.0 302, 5663 GO:0019901 MF e protein kinase binding 6/100 654/19669 0.1498491063849149 5 6 1.0 60, 4137, 4217, 5071, 5580, 50507 GO:0019955 MF e cytokine binding 2/100 136/19669 0.1521825177535301 3 2 1.0 3146, 729230 GO:0009055 MF e electron transfer activity 2/100 136/19669 0.1521825177535301 3 2 1.0 4199, 50507 GO:0035257 MF e nuclear hormone receptor binding 2/100 140/19669 0.1592828759255446 6 2 1.0 5468, 9971 GO:0003677 MF e DNA binding 17/100 2449/19669 0.1709518517249829 4 17 1.0 60, 196, 213, 351, 2023, 3146, 4137, 4780, 4831, 4851, 5465, 5468, 5591, 6622, 9131, 9971, 136319 GO:0046943 MF e carboxylic acid transmembrane transporter activity 2/100 152/19669 0.1809289969631957 6 2 1.0 1244, 5243 GO:0005342 MF e organic acid transmembrane transporter activity 2/100 153/19669 0.1827532509311823 5 2 1.0 1244, 5243 GO:0001227 MF e DNA-binding transcription repressor activity, RNA polymerase II-specific 3/100 306/19669 0.2040701429473292 4 3 1.0 2023, 5465, 5468 GO:0016874 MF e ligase activity 2/100 165/19669 0.2048404010448343 2 2 1.0 2180, 5091 GO:0001217 MF e DNA-binding transcription repressor activity 3/100 308/19669 0.2066884861182873 3 3 1.0 2023, 5465, 5468 GO:0051427 MF e hormone receptor binding 2/100 173/19669 0.2197272759020458 4 2 1.0 5468, 9971 GO:0046982 MF e protein heterodimerization activity 3/100 321/19669 0.2238894979707628 4 3 1.0 196, 581, 3654 GO:0008237 MF e metallopeptidase activity 2/100 183/19669 0.2384598421742121 4 2 1.0 4313, 4318 GO:0008233 MF e peptidase activity 5/100 615/19669 0.2449860538852012 3 5 1.0 1510, 4313, 4318, 5327, 5663 GO:0051015 MF e actin filament binding 2/100 208/19669 0.2855362415388915 5 2 1.0 2934, 10096 GO:0016887 MF e ATPase activity 4/100 466/19669 0.3032971872219855 7 4 1.0 1244, 2180, 3309, 5243 GO:0017111 MF e nucleoside-triphosphatase activity 6/100 832/19669 0.3200380705167386 6 6 1.0 1244, 2180, 3309, 5243, 7846, 10383 GO:0042393 MF e histone binding 2/100 239/19669 0.3434859928409092 3 2 1.0 6622, 23476 GO:0003690 MF e double-stranded DNA binding 11/100 1656/19669 0.3631400278167554 5 11 1.0 196, 351, 2023, 3146, 4137, 4780, 5465, 5468, 5591, 6622, 9971 GO:0043565 MF e sequence-specific DNA binding 11/100 1665/19669 0.3647428683332279 5 11 1.0 196, 351, 2023, 3146, 4137, 4780, 5465, 5468, 6622, 9971, 136319 GO:0003682 MF e chromatin binding 4/100 552/19669 0.3663562627914373 2 4 1.0 60, 4851, 5468, 23476 GO:0008017 MF e microtubule binding 2/100 267/19669 0.3945557974539352 5 2 1.0 4137, 81631 GO:0140110 MF e transcription regulator activity 12/100 1905/19669 0.3974944898674834 1 12 1.0 196, 2023, 3146, 4780, 4831, 4851, 5071, 5465, 5468, 9971, 11035, 23476 GO:0016757 MF e transferase activity, transferring glycosyl groups 2/100 272/19669 0.4034969786875516 3 2 1.0 4860, 5836 GO:0032550 MF e purine ribonucleoside binding 3/100 376/19669 0.4435213487079341 5 3 1.0 4831, 7846, 10383 GO:0032549 MF e ribonucleoside binding 3/100 379/19669 0.4454573686646387 4 3 1.0 4831, 7846, 10383 GO:0001883 MF e purine nucleoside binding 3/100 379/19669 0.4454573686646387 4 3 1.0 4831, 7846, 10383 GO:0003676 MF e nucleic acid binding 23/100 3914/19669 0.4508320058928935 3 23 1.0 60, 196, 213, 302, 351, 821, 1719, 2023, 2194, 2896, 3146, 4137, 4780, 4831, 4851, 5465, 5468, 5591, 6622, 9131, 9971, 10383, 136319 GO:0032561 MF e guanyl ribonucleotide binding 3/100 393/19669 0.4549691734599006 7 3 1.0 4831, 7846, 10383 GO:0019001 MF e guanyl nucleotide binding 3/100 393/19669 0.4549691734599006 6 3 1.0 4831, 7846, 10383 GO:0016462 MF e pyrophosphatase activity 6/100 885/19669 0.4612228353933167 5 6 1.0 1244, 2180, 3309, 5243, 7846, 10383 GO:0016818 MF e hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 6/100 887/19669 0.4618549214996692 4 6 1.0 1244, 2180, 3309, 5243, 7846, 10383 GO:0016817 MF e hydrolase activity, acting on acid anhydrides 6/100 887/19669 0.4618549214996692 3 6 1.0 1244, 2180, 3309, 5243, 7846, 10383 GO:0001228 MF e DNA-binding transcription activator activity, RNA polymerase II-specific 3/100 442/19669 0.4932334895430014 4 3 1.0 4780, 5465, 9971 GO:0001216 MF e DNA-binding transcription activator activity 3/100 446/19669 0.4966211716797555 3 3 1.0 4780, 5465, 9971 GO:0015267 MF e channel activity 3/100 476/19669 0.5228940920475623 4 3 1.0 302, 581, 5663 GO:0005215 MF e transporter activity 7/100 1157/19669 0.5272601199031393 1 7 1.0 302, 335, 348, 581, 1244, 5243, 5663 GO:0000976 MF e transcription regulatory region sequence-specific DNA binding 9/100 1502/19669 0.5698371967483047 7 9 1.0 196, 351, 2023, 3146, 4780, 5465, 5468, 6622, 9971 GO:0001067 MF e regulatory region nucleic acid binding 9/100 1503/19669 0.5700299245247751 4 9 1.0 196, 351, 2023, 3146, 4780, 5465, 5468, 6622, 9971 GO:0003723 MF e RNA binding 10/100 1652/19669 0.5850396634108692 4 10 1.0 302, 821, 1719, 2023, 2194, 2896, 3146, 4137, 5591, 10383 GO:0022804 MF e active transmembrane transporter activity 2/100 298/19669 0.6653595627656298 3 2 1.0 1244, 5243 GO:0003924 MF e GTPase activity 2/100 317/19669 0.6770599695809351 7 2 1.0 7846, 10383 GO:0005261 MF e cation channel activity 2/100 333/19669 0.6874972196158685 6 2 1.0 302, 5663 GO:1990837 MF e sequence-specific double-stranded DNA binding 9/100 1565/19669 0.7090576500112904 6 9 1.0 196, 351, 2023, 3146, 4780, 5465, 5468, 6622, 9971 GO:0005525 MF e GTP binding 2/100 371/19669 0.7135894008873576 8 2 1.0 7846, 10383 GO:0022803 MF e passive transmembrane transporter activity 3/100 477/19669 0.7369555644399852 3 3 1.0 302, 581, 5663 GO:0016788 MF e hydrolase activity, acting on ester bonds 4/100 734/19669 0.7896040314953432 3 4 1.0 2081, 2194, 3162, 9104 GO:0004888 MF p transmembrane signaling receptor activity 3/100 1262/19669 0.2169639139770001 3 3 1.0 4851, 5468, 729230 GO:0038023 MF p signaling receptor activity 5/100 1454/19669 0.4461965560293857 2 5 1.0 4851, 5465, 5468, 9971, 729230 GO:0060089 MF p molecular transducer activity 5/100 1454/19669 0.4461965560293857 1 5 1.0 4851, 5465, 5468, 9971, 729230 GO:0004930 MF p G protein-coupled receptor activity 2/100 835/19669 0.4485242999998086 4 2 1.0 5468, 729230 GO:0008324 MF p cation transmembrane transporter activity 2/100 625/19669 0.7731702578956992 4 2 1.0 302, 5663 GO:0000981 MF p DNA-binding transcription factor activity, RNA polymerase II-specific 6/100 1375/19669 0.8451073517443723 3 6 1.0 196, 2023, 4780, 5465, 5468, 9971 GO:0003700 MF p DNA-binding transcription factor activity 6/100 1427/19669 0.8458786055377181 2 6 1.0 196, 2023, 4780, 5465, 5468, 9971 GO:0000977 MF p RNA polymerase II transcription regulatory region sequence-specific DNA binding 7/100 1408/19669 1.0 8 7 1.0 196, 351, 2023, 4780, 5465, 5468, 9971 GO:0015318 MF p inorganic molecular entity transmembrane transporter activity 4/100 818/19669 1.0 3 4 1.0 302, 1244, 5243, 5663 GO:0015075 MF p ion transmembrane transporter activity 4/100 933/19669 1.0 3 4 1.0 302, 1244, 5243, 5663 GO:0008509 MF p anion transmembrane transporter activity 2/100 452/19669 1.0 4 2 1.0 1244, 5243 GO:0000987 MF p cis-regulatory region sequence-specific DNA binding 6/100 1210/19669 1.0 8 6 1.0 196, 351, 4780, 5465, 5468, 9971 GO:0000978 MF p RNA polymerase II cis-regulatory region sequence-specific DNA binding 6/100 1191/19669 1.0 9 6 1.0 196, 351, 4780, 5465, 5468, 9971 GO:0022890 MF p inorganic cation transmembrane transporter activity 2/100 578/19669 1.0 5 2 1.0 302, 5663 GO:0005216 MF p ion channel activity 2/100 429/19669 1.0 5 2 1.0 302, 5663 GO:0046873 MF p metal ion transmembrane transporter activity 2/100 423/19669 1.0 6 2 1.0 302, 5663 GO:0022857 MF p transmembrane transporter activity 5/100 1048/19669 1.0 2 5 1.0 302, 581, 1244, 5243, 5663